By Catron D., Zlotnik A.
CTACK/CCL27 is a member of the b or CC kin of chemokines. it's came across on human chromosome 9p13 and on murine chromosome four. CCL27 is distinctive from different chemokines in different methods: (1) its gene is found at the contrary interpreting body overlapping the gene encoding the a sequence of the interleukin eleven receptor (Baird et aL, 1999; Ishikawa-Mochizuki et al, 1999) and (2) it's particularly expressed in pores and skin by means of keratinocytes (Morales et al, 1999). even if on the other hand spliced types also are expressed in testis, center, and liver (Hromas et al, 1999). CCL27 chemo-attracts CLA+ reminiscence T cells. The CCL27 receptor is CCR10 (formerly often called GPR2) (Homey et al, 2000; Jarmin et al, 2000).
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