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Extra resources for Arsenic Exposure and Health Effects III. Proceedings of the Third International Conference on Arsenic Exposure and Health Effects, July 12–15, 1998, San Diego, California

Sample text

For daily personal samples, airborne particle size distribution samples were collected by use of a battery-powered personal air sampling pump (Gilian® Model HFS 113A) connected to a six-stage personal cascade impactor (Marple® Model 296). Cascade impactor filters were desiccated and weighed on the microbalance prior to sampling. Gravimetric and arsenic analyses were carried out on each filter as described below. Analysis of Air Samples Gravimetric Method for Total Dust Filters were weighed on a six-place microbalance (Cahn Instruments) following a 48-hr desiccation period.

1981). When As has been ingested chronically for years, longer periods of clean water use appear necessary to restore a background urinary excretion. Intervention studies (Hopenhayn-Rich et al. , 1997) show that the consumption during 2 months of water with 45 /ig As/L instead of 600 \L^Jh reduces the urinary excretion from 636 to 166 /xg/L. , 1998). , 1997) the restoration of a normal urinary excretion of As may require a few years. DISCUSSION AND CONCLUSIONS The use of As levels in hair and nails as indices of internal exposure intensity is of potential interest but there is a clear need for a well standardized analytical procedure for these determinations.

And Pershagen, C 1991. Arsenic exposure, smoking, and lung cancer in smelter workers—a case-control study. Am. J. Epidemiol, 134,545-551. W. , and Vahter, M. 1996. A physiologically based pharmacokinetic model for arsenic exposure, n. Validation and application in humans. Toxicol Appl. Pharmacol, 140,471-486. J. G. 1995. Particle inhalability curves for humans and small laboratory animals. Ann. Occup. , 19,317-328. , Boeckx, M. and Lauwerys, R. 1992. Relation between airborne arsenic trioxide and urinary excretion of inorganic arsenic and its methylated metabolites.

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