By David T Suzuki
It is a revision of the genetics textual content, thoroughly up to date and reorganized to mirror the swift developments within the genetics box. The fourth variation simplifies the presentation of inauspicious suggestions with no compromising the text's medical integrity
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Additional info for An Introduction to genetic analysis
Plants from green F2 peas were also grown and selfed and were found to bear only green peas. In summary, all the F2 green peas were evidently pure-breeding, like the green parental line, but, of the F2 yellow peas, twothirds were like the F1 yellow peas (producing yellow and green seeds in a 3 : 1 ratio) and one-third were like the pure-breeding yellow parent. Thus the study of the individual selfings revealed that underlying the 3 : 1 Results of All Mendel’s Crosses in Which Parents Differed in One Character Parental phenotype 1.
A key part of the model is the nature of the F1 individuals, which are proposed to carry two different alleles, and these segregate equally into gametes. Therefore Mendel took an F1 plant (that grew from a yellow seed) and crossed it with a plant grown from a green seed. The principle of equal segregation means that a 1 : 1 ratio of yellow to green seeds could be predicted in the next generation. If we let Y stand for the allele that determines the dominant phenotype (yellow seeds) and y stand for the allele that determines the recessive phenotype (green seeds), we can diagram Mendel’s predictions, as shown in Figure 2-8.
Huntington disease is another example of a disease inherited as a dominant phenotype determined by an allele of a single gene. The phenotype is one of neural degeneration, leading to convulsions and premature death. Figure 2-15 The human pseudoachondroplasia phenotype, illustrated by a family of five sisters and two brothers. The phenotype is determined by a dominant allele, which we can call D, that interferes with bone growth during development. This photograph was taken upon the arrival of the family in Israel after the end of the Second World War.