By Dr. Adam Schneeweiss, Dr. Marija Weiss (auth.)

Show description

Read or Download Advances in Nitrate Therapy PDF

Similar therapy books

Wörterbuch der Psychotherapie (German Edition)

Das "Wörterbuch der Psychotherapie" beschreibt methodenübergreifend und methodenbezogen in 1315 Stichwörtern die wesentlichen Begriffe der modernen Psychotherapie. 360 Autoren/innen aus 14 Ländern haben sich an diesem Werk beteiligt, das fifty one Fachbereiche bzw. psychotherapeutische Ansätze einbezieht. Die Begriffe sind mit Querverweisen vernetzt und bieten 4500 weiterführende Quellenangaben.

Occupational Therapy and Life Course Development: A Work Book for Professional Practice

Occupational treatment and existence direction improvement is a useful paintings e-book for pro perform. It presents a device to aid either scholars and certified execs enhance and improve a framework for his or her perform that helps all participants and settings in a holistic and inclusive means. a lot of the publication is organised as a piece ebook dependent round a unmarried case examine.

Your Bones: How You Can Prevent Osteoporosis and Have Strong Bones for Life - Naturally

Your Bones comprises every thing you must be aware of for fit bones in a single e-book, offering scientifically established suggestion which highlights normal prevention and remedy ideas. This up-to-date AND improved version comprises many new reviews at the risks of the bisphosphonate medications and a detailed dialogue of 2 new medicinal drugs with strength hostile results.

Additional resources for Advances in Nitrate Therapy

Sample text

The antianginal effect was associated with a decrease of 14 mmHg in systolic arterial pressure and an increase of 3 beats/min in heart rate. Diastolic arterial pressure was not altered. This is a most important safety factor in patients with coronary artery disease, in whom reduction in coronary arterial pressure is deleterious. Raffienbeul et al [73] compared the effects of nifedipine, administered intravenously at a rate of 15-30 mg124 h, and nitroglycerin, administered intravenously at a rate of 30-60 mg124 h, over a 72-h observation period in 20 patients with angina pectoris at rest.

Parker and coworkers have consistently reported that the antianginal effect of nitrates was abolished during continued treatment of up to 2 weeks [114, 115]. The most recent studies from this group, however, used long-acting formulations of nitrates, namely transdermal nitroglycerin disks and ISDN ointment, which might have special problems. The possibility of tolerance to transdermally administered nitrates is discussed separately in the chapter on this topic. Studies on Long-Term Use of Nitrates in Angina Pectoris 39 long-term use of new nitrate formulations will clarify this point.

In contrast, patients receiving nitroglycerin required progressively higher doses. The most common adverse effect was hypotension - in 14% of the patients on nitroglycerin and 8% on ISDN. 2. Effect on Size and Complications of Acute Myocardial Infarction The anti-ischemic effects of nitrates can result in a decrease in infarct size. This has been demonstrated in experimental and clinical studies, using pathologic, enzymatic and electrocardiographic evaluation ofinfarct size [130-137]. In many of these studies it was shown that maintenance of adequate coronary perfusion pressure is essential for the beneficial effect.

Download PDF sample

Rated 4.86 of 5 – based on 7 votes